As we enter the second decade of the 21st century, we are challenged by unprecedented planetary-scale events—resource wars, climate change, emerging diseases—which increase in frequency and pose unprecedented problems for mapping and design. Additionally, due to everyday revolutions in communications, computation, biotech, and nanotech, we face, statistically speaking, a range of existential risks that could transform or eradicate humanity and irrevocably alter all the systems on our planet. Design and Existential Risk is a series of conversations with leading thinkers, designers, authors and educators, critically questioning how the practice of design can imagine and prepare for extreme existential risks.